ENSG00000169385


Homo sapiens

Features
Gene ID: ENSG00000169385
  
Biological name :RNASE2
  
Synonyms : P10153 / ribonuclease A family member 2 / RNASE2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 20955452
Gene end: 20956436
  
Corresponding Affymetrix probe sets: 206111_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000303276
NCBI entrez gene - 6036     See in Manteia.
OMIM - 131410
RefSeq - NM_002934
RefSeq Peptide - NP_002925
swissprot - P10153
swissprot - W0UV60
Ensembl - ENSG00000169385
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ear1ENSMUSG00000072601Mus musculus
 Ear10ENSMUSG00000090166Mus musculus
 Ear14ENSMUSG00000050766Mus musculus
 Ear2ENSMUSG00000072596Mus musculus
 Ear6ENSMUSG00000062148Mus musculus
 O35292ENSMUSG00000059606Mus musculus
 Rnase2aENSMUSG00000047222Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P12724 / RNASE3 / ribonuclease A family member 3ENSG0000016939769
Q8TDE3 / RNASE8 / ribonuclease A family member 8ENSG0000017343141
Q93091 / RNASE6 / ribonuclease A family member k6ENSG0000016941340
Q9H1E1 / RNASE7 / ribonuclease A family member 7ENSG0000016579939


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023411  Ribonuclease A, active site
 IPR023412  Ribonuclease A-domain
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006401 RNA catabolic process TAS
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IDA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IBA
 molecular_functionGO:0004522 ribonuclease A activity IEA
 molecular_functionGO:0004540 ribonuclease activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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