ENSG00000170500


Homo sapiens

Features
Gene ID: ENSG00000170500
  
Biological name :LONRF2
  
Synonyms : LON peptidase N-terminal domain and ring finger 2 / LONRF2 / Q1L5Z9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q11.2
Gene start: 100273291
Gene end: 100322733
  
Corresponding Affymetrix probe sets: 225996_at (Human Genome U133 Plus 2.0 Array)   235977_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377086
Ensembl peptide - ENSP00000386823
NCBI entrez gene - 164832     See in Manteia.
RefSeq - NM_198461
RefSeq Peptide - NP_940863
swissprot - Q1L5Z9
Ensembl - ENSG00000170500
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch1073-440b2.1ENSDARG00000089138Danio rerio
 LONRF2ENSGALG00000016768Gallus gallus
 Lonrf2ENSMUSG00000048814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LONRF3 / Q496Y0 / LON peptidase N-terminal domain and ring finger 3ENSG0000017555634
LONRF1 / Q17RB8 / LON peptidase N-terminal domain and ring finger 1ENSG0000015435932


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR003111  Lon, substrate-binding domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015947  PUA-like superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019734  Tetratricopeptide repeat
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0005622 intracellular IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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