ENSG00000154359


Homo sapiens

Features
Gene ID: ENSG00000154359
  
Biological name :LONRF1
  
Synonyms : LON peptidase N-terminal domain and ring finger 1 / LONRF1 / Q17RB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p23.1
Gene start: 12721894
Gene end: 12756073
  
Corresponding Affymetrix probe sets: 215322_at (Human Genome U133 Plus 2.0 Array)   226038_at (Human Genome U133 Plus 2.0 Array)   236556_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433327
Ensembl peptide - ENSP00000451692
Ensembl peptide - ENSP00000436770
Ensembl peptide - ENSP00000434090
Ensembl peptide - ENSP00000381298
Ensembl peptide - ENSP00000432130
NCBI entrez gene - 91694     See in Manteia.
RefSeq - XM_011544694
RefSeq - NM_152271
RefSeq - XM_005273685
RefSeq Peptide - NP_689484
swissprot - H7C5V9
swissprot - E9PRX6
swissprot - Q17RB8
swissprot - E9PQH4
swissprot - A0A0C4DGE8
Ensembl - ENSG00000154359
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lonrf1lENSDARG00000078567Danio rerio
 LONRF1ENSGALG00000013725Gallus gallus
 Lonrf1ENSMUSG00000039633Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LONRF3 / Q496Y0 / LON peptidase N-terminal domain and ring finger 3ENSG0000017555636
LONRF2 / Q1L5Z9 / LON peptidase N-terminal domain and ring finger 2ENSG0000017050032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR003111  Lon, substrate-binding domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015947  PUA-like superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019734  Tetratricopeptide repeat
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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