ENSG00000170873


Homo sapiens

Features
Gene ID: ENSG00000170873
  
Biological name :MTSS1
  
Synonyms : MTSS1 / MTSS1, I-BAR domain containing / O43312
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.13
Gene start: 124550790
Gene end: 124728429
  
Corresponding Affymetrix probe sets: 203036_s_at (Human Genome U133 Plus 2.0 Array)   203037_s_at (Human Genome U133 Plus 2.0 Array)   210359_at (Human Genome U133 Plus 2.0 Array)   210360_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428685
Ensembl peptide - ENSP00000428348
Ensembl peptide - ENSP00000429064
Ensembl peptide - ENSP00000429752
Ensembl peptide - ENSP00000322804
Ensembl peptide - ENSP00000367256
Ensembl peptide - ENSP00000393606
Ensembl peptide - ENSP00000428145
Ensembl peptide - ENSP00000428319
NCBI entrez gene - 9788     See in Manteia.
OMIM - 608486
RefSeq - XM_017014101
RefSeq - XM_017014092
RefSeq - XM_017014093
RefSeq - XM_017014094
RefSeq - XM_017014095
RefSeq - XM_017014096
RefSeq - XM_017014097
RefSeq - XM_017014098
RefSeq - XM_017014099
RefSeq - XM_017014100
RefSeq - NM_001282971
RefSeq - NM_001282974
RefSeq - NM_014751
RefSeq - XM_005251111
RefSeq - XM_005251113
RefSeq - XM_005251118
RefSeq - XM_006716700
RefSeq - XM_006716701
RefSeq - XM_006716702
RefSeq - XM_006716703
RefSeq - XM_006716704
RefSeq - XM_006716705
RefSeq - XM_006716706
RefSeq - XM_011517403
RefSeq - XM_011517404
RefSeq - XM_017014086
RefSeq - XM_017014087
RefSeq - XM_017014088
RefSeq - XM_017014089
RefSeq - XM_017014090
RefSeq - XM_017014091
RefSeq Peptide - NP_001269903
RefSeq Peptide - NP_055566
RefSeq Peptide - NP_001269900
swissprot - H0YBL3
swissprot - E7EWW5
swissprot - O43312
swissprot - E5RJX3
swissprot - H0YAZ8
swissprot - H0YB53
Ensembl - ENSG00000170873
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTSS1ENSGALG00000041969Gallus gallus
 Mtss1ENSMUSG00000022353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTSS1L / Q765P7 / MTSS1L, I-BAR domain containingENSG0000013261356


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR013606  IMD/I-BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR027682  I-BAR domain containing protein MIM
 IPR030127  I-BAR domain containing protein MIM/ABBA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007009 plasma membrane organization IEA
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS
 biological_processGO:0030035 microspike assembly NAS
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation ISS
 biological_processGO:0061333 renal tubule morphogenesis ISS
 biological_processGO:0071498 cellular response to fluid shear stress ISS
 biological_processGO:0072102 glomerulus morphogenesis ISS
 biological_processGO:0072160 nephron tubule epithelial cell differentiation ISS
 biological_processGO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis ISS
 cellular_componentGO:0001726 ruffle NAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0030139 endocytic vesicle TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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