ENSG00000171033


Homo sapiens

Features
Gene ID: ENSG00000171033
  
Biological name :PKIA
  
Synonyms : cAMP-dependent protein kinase inhibitor alpha / P61925 / PKIA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q21.13
Gene start: 78516139
Gene end: 78605267
  
Corresponding Affymetrix probe sets: 204612_at (Human Genome U133 Plus 2.0 Array)   226864_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430887
Ensembl peptide - ENSP00000336552
Ensembl peptide - ENSP00000379696
NCBI entrez gene - 5569     See in Manteia.
OMIM - 606059
RefSeq - XM_017013622
RefSeq - NM_006823
RefSeq - NM_181839
RefSeq - XM_017013620
RefSeq - XM_017013621
RefSeq Peptide - NP_006814
RefSeq Peptide - NP_862822
swissprot - P61925
swissprot - A0A024R7Y9
Ensembl - ENSG00000171033
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKIAENSGALG00000035525Gallus gallus
 PkiaENSMUSG00000027499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004171  cAMP-dependent protein kinase inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042308 negative regulation of protein import into nucleus IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 biological_processGO:2000480 negative regulation of cAMP-dependent protein kinase activity IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IEA
 molecular_functionGO:0004862 cAMP-dependent protein kinase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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