ENSG00000171243


Homo sapiens

Features
Gene ID: ENSG00000171243
  
Biological name :SOSTDC1
  
Synonyms : Q6X4U4 / sclerostin domain containing 1 / SOSTDC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.1
Gene start: 16461481
Gene end: 16530580
  
Corresponding Affymetrix probe sets: 213456_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304930
Ensembl peptide - ENSP00000379889
NCBI entrez gene - 25928     See in Manteia.
OMIM - 609675
RefSeq - NM_015464
RefSeq - XM_017011943
RefSeq Peptide - NP_056279
swissprot - A4D125
swissprot - Q6X4U4
Ensembl - ENSG00000171243
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sostdc1aENSDARG00000068892Danio rerio
 ENSGALG00000034685Gallus gallus
 Q6VYA3ENSGALG00000036836Gallus gallus
 Q9CQN4ENSMUSG00000036169Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOST / Q9BQB4 / sclerostinENSG0000016794138


Protein motifs (from Interpro)
Interpro ID Name
 IPR006207  Cystine knot, C-terminal
 IPR008835  Sclerostin/Sclerostin domain-containing protein 1
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0010454 negative regulation of cell fate commitment IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IDA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IDA
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IDA
 biological_processGO:0060648 mammary gland bud morphogenesis IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000016 negative regulation of determination of dorsal identity IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0036122 BMP binding IDA
 molecular_functionGO:0098821 BMP receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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