ENSG00000171951


Homo sapiens

Features
Gene ID: ENSG00000171951
  
Biological name :SCG2
  
Synonyms : P13521 / SCG2 / secretogranin II
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q36.1
Gene start: 223596940
Gene end: 223602503
  
Corresponding Affymetrix probe sets: 204035_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304133
Ensembl peptide - ENSP00000415468
Ensembl peptide - ENSP00000394702
NCBI entrez gene - 7857     See in Manteia.
OMIM - 118930
RefSeq - NM_003469
RefSeq Peptide - NP_003460
swissprot - C9JQI2
swissprot - C9JDT0
swissprot - P13521
Ensembl - ENSG00000171951
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scg2bENSDARG00000038574Danio rerio
 SCG2ENSGALG00000029819Gallus gallus
 Scg2ENSMUSG00000050711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001990  Chromogranin A/B/C
 IPR018054  Chromogranin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IDA
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001937 negative regulation of endothelial cell proliferation TAS
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0009306 protein secretion TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0043542 endothelial cell migration TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0048245 eosinophil chemotaxis IDA
 biological_processGO:0050918 positive chemotaxis IDA
 biological_processGO:0050930 induction of positive chemotaxis IDA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IDA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0098992 neuronal dense core vesicle IEA
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042056 chemoattractant activity IDA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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