ENSMUSG00000050711


Mus musculus

Features
Gene ID: ENSMUSG00000050711
  
Biological name :Scg2
  
Synonyms : Q03517 / Scg2 / secretogranin II
  
Possible biological names infered from orthology : P13521
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C4
Gene start: 79434669
Gene end: 79440120
  
Corresponding Affymetrix probe sets: 10355960 (MoGene1.0st)   1450708_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062556
Ensembl peptide - ENSMUSP00000139740
NCBI entrez gene - 20254     See in Manteia.
MGI - MGI:103033
RefSeq - NM_009129
RefSeq - NM_001310680
RefSeq Peptide - NP_001297609
RefSeq Peptide - NP_033155
swissprot - Q03517
swissprot - Q4W8U9
Ensembl - ENSMUSG00000050711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scg2bENSDARG00000038574Danio rerio
 SCG2ENSGALG00000029819Gallus gallus
 SCG2ENSG00000171951Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001990  Chromogranin A/B/C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISS
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0048245 eosinophil chemotaxis IEA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0050930 induction of positive chemotaxis IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0031045 dense core granule IDA
 cellular_componentGO:0098992 neuronal dense core vesicle IDA
 molecular_functionGO:0005125 cytokine activity ISS
 molecular_functionGO:0042056 chemoattractant activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003898 abnormal QRS complex "anomaly in the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarise prior to their contraction" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Rock1tm1b(NCOM)Mfgc/Rock1tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Rock1tm1b(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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