ENSG00000171989


Homo sapiens

Features
Gene ID: ENSG00000171989
  
Biological name :LDHAL6B
  
Synonyms : lactate dehydrogenase A like 6B / LDHAL6B / Q9BYZ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q22.2
Gene start: 59206823
Gene end: 59208515
  
Corresponding Affymetrix probe sets: 210712_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302393
NCBI entrez gene - 92483     See in Manteia.
RefSeq - NM_033195
RefSeq Peptide - NP_149972
swissprot - A0A140VJM9
swissprot - Q9BYZ2
Ensembl - ENSG00000171989
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ldhaENSDARG00000101251Danio rerio
 LDHAENSGALG00000006300Gallus gallus
 Ldhal6bENSMUSG00000101959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZMR3 / LDHAL6A / lactate dehydrogenase A like 6AENSG0000016680072
LDHA / P00338 / lactate dehydrogenase AENSG0000013433363
LDHC / P07864 / lactate dehydrogenase CENSG0000016679659
LDHB / P07195 / lactate dehydrogenase BENSG0000011171658
UEVLD / Q8IX04 / UEV and lactate/malate dehyrogenase domainsENSG0000015111635


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001557  L-lactate/malate dehydrogenase
 IPR011304  L-lactate dehydrogenase
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR018177  L-lactate dehydrogenase, active site
 IPR022383  Lactate/malate dehydrogenase, C-terminal
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006090 pyruvate metabolic process TAS
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004459 L-lactate dehydrogenase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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