ENSG00000166796


Homo sapiens

Features
Gene ID: ENSG00000166796
  
Biological name :LDHC
  
Synonyms : lactate dehydrogenase C / LDHC / P07864
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.1
Gene start: 18412307
Gene end: 18452058
  
Corresponding Affymetrix probe sets: 207022_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443414
Ensembl peptide - ENSP00000441991
Ensembl peptide - ENSP00000443997
Ensembl peptide - ENSP00000280704
Ensembl peptide - ENSP00000379518
Ensembl peptide - ENSP00000437783
Ensembl peptide - ENSP00000438196
Ensembl peptide - ENSP00000439060
Ensembl peptide - ENSP00000439555
Ensembl peptide - ENSP00000441478
NCBI entrez gene - 3948     See in Manteia.
OMIM - 150150
RefSeq - XM_017017722
RefSeq - NM_002301
RefSeq - NM_017448
RefSeq - XM_017017721
RefSeq Peptide - NP_059144
RefSeq Peptide - NP_002292
swissprot - F5H5G7
swissprot - G3XAP5
swissprot - P07864
swissprot - A0A140VKA7
swissprot - F5GWS6
swissprot - F5GZ11
swissprot - F5H245
swissprot - F5H155
swissprot - F5H326
Ensembl - ENSG00000166796
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ldhaENSDARG00000101251Danio rerio
 LDHAENSGALG00000006300Gallus gallus
 LdhcENSMUSG00000030851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LDHA / P00338 / lactate dehydrogenase AENSG0000013433376
LDHB / P07195 / lactate dehydrogenase BENSG0000011171670
Q9BYZ2 / LDHAL6B / lactate dehydrogenase A like 6BENSG0000017198967
Q6ZMR3 / LDHAL6A / lactate dehydrogenase A like 6AENSG0000016680066
UEVLD / Q8IX04 / UEV and lactate/malate dehyrogenase domainsENSG0000015111638


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001557  L-lactate/malate dehydrogenase
 IPR011304  L-lactate dehydrogenase
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR018177  L-lactate dehydrogenase, active site
 IPR022383  Lactate/malate dehydrogenase, C-terminal
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006090 pyruvate metabolic process TAS
 biological_processGO:0006754 ATP biosynthetic process IEA
 biological_processGO:0019244 lactate biosynthetic process from pyruvate IEA
 biological_processGO:0019516 lactate oxidation IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004459 L-lactate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166796 LDHC / P07864 / lactate dehydrogenase C  / complex






 

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