ENSG00000172020


Homo sapiens

Features
Gene ID: ENSG00000172020
  
Biological name :GAP43
  
Synonyms : GAP43 / growth associated protein 43 / P17677
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.31
Gene start: 115623324
Gene end: 115721490
  
Corresponding Affymetrix probe sets: 204471_at (Human Genome U133 Plus 2.0 Array)   216963_s_at (Human Genome U133 Plus 2.0 Array)   216967_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305010
Ensembl peptide - ENSP00000377372
NCBI entrez gene - 2596     See in Manteia.
OMIM - 162060
RefSeq - XM_017006128
RefSeq - NM_001130064
RefSeq - NM_002045
RefSeq Peptide - NP_002036
RefSeq Peptide - NP_001123536
swissprot - P17677
swissprot - Q5U058
Ensembl - ENSG00000172020
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gap43ENSDARG00000099744Danio rerio
 GAP43ENSGALG00000015089Gallus gallus
 Gap43ENSMUSG00000047261Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001422  Neuromodulin (GAP-43)
 IPR017454  Neuromodulin (GAP-43), C-terminal
 IPR018243  Neuromodulin, palmitoylation site
 IPR018947  Neuromodulin gap junction N-terminal
 IPR033137  Neuromodulin, phosphorylation site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0009611 response to wounding TAS
 biological_processGO:0010001 glial cell differentiation IEA
 biological_processGO:0016198 axon choice point recognition IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0042246 tissue regeneration IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0051489 regulation of filopodium assembly IDA
 biological_processGO:0061564 axon development IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0031527 filopodium membrane IEA
 cellular_componentGO:0032584 growth cone membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0035727 lysophosphatidic acid binding IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IEA


Pathways (from Reactome)
Pathway description
L1CAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011009 LYPLA2 / O95372 / lysophospholipase II  / reaction






 

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