ENSG00000172367


Homo sapiens

Features
Gene ID: ENSG00000172367
  
Biological name :PDZD3
  
Synonyms : PDZD3 / PDZ domain containing 3 / Q86UT5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.3
Gene start: 119185457
Gene end: 119190223
  
Corresponding Affymetrix probe sets: 1555490_s_at (Human Genome U133 Plus 2.0 Array)   220303_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434559
Ensembl peptide - ENSP00000327107
Ensembl peptide - ENSP00000347742
Ensembl peptide - ENSP00000431164
Ensembl peptide - ENSP00000434264
NCBI entrez gene - 79849     See in Manteia.
OMIM - 607146
RefSeq - XM_017018335
RefSeq - NM_024791
RefSeq - XM_011543000
RefSeq - XM_011543001
RefSeq - XM_011543002
RefSeq - XM_011543005
RefSeq - XM_017018334
RefSeq - NM_001168468
RefSeq Peptide - NP_001161940
RefSeq Peptide - NP_079067
swissprot - E9PRB0
swissprot - E9PPZ1
swissprot - Q86UT5
swissprot - B0YJ61
Ensembl - ENSG00000172367
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdzd3aENSDARG00000040568Danio rerio
 pdzd3bENSDARG00000055656Danio rerio
 PDZD3ENSGALG00000006779Gallus gallus
 Pdzd3ENSMUSG00000032105Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDZK1 / Q5T2W1 / PDZ domain containing 1ENSG0000017482730
Q15599 / SLC9A3R2 / SLC9A3 regulator 2ENSG0000006505420
O14745 / SLC9A3R1 / SLC9A3 regulator 1ENSG0000010906219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR031200  Na(+)/H(+) exchange regulatory cofactor NHERF-4
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport NAS
 biological_processGO:0006833 water transport NAS
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IC
 biological_processGO:0009636 response to toxic substance TAS
 biological_processGO:0019934 cGMP-mediated signaling NAS
 biological_processGO:0030827 obsolete negative regulation of cGMP biosynthetic process TAS
 biological_processGO:0031283 negative regulation of guanylate cyclase activity IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005903 brush border IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0035003 subapical complex IDA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0008200 ion channel inhibitor activity TAS
 molecular_functionGO:0030251 guanylate cyclase inhibitor activity IDA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
Intestinal infectious diseases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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