ENSMUSG00000032105


Mus musculus

Features
Gene ID: ENSMUSG00000032105
  
Biological name :Pdzd3
  
Synonyms : Pdzd3 / PDZ domain containing 3
  
Possible biological names infered from orthology : Q86UT5
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.2
Gene start: 44247307
Gene end: 44251471
  
Corresponding Affymetrix probe sets: 10592752 (MoGene1.0st)   1449330_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034618
NCBI entrez gene - 170761     See in Manteia.
MGI - MGI:2429554
RefSeq - NM_133226
RefSeq Peptide - NP_573489
swissprot - A0A0R4J0D4
Ensembl - ENSMUSG00000032105
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdzd3aENSDARG00000040568Danio rerio
 pdzd3bENSDARG00000055656Danio rerio
 PDZD3ENSGALG00000006779Gallus gallus
 PDZD3ENSG00000172367Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pdzk1 / Na(+)/H(+) exchange regulatory cofactor NHE-RF3 / Q5T2W1* / PDZ domain containing 1*ENSMUSG0000003829828
P70441 / Slc9a3r1 / solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 / O14745* / SLC9A3 regulator 1*ENSMUSG0000002073319
Slc9a3r2 / solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 / Q15599* / SLC9A3 regulator 2*ENSMUSG0000000250419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR031200  Na(+)/H(+) exchange regulatory cofactor NHERF-4
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IEA
 biological_processGO:0031283 negative regulation of guanylate cyclase activity IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0035003 subapical complex IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0030251 guanylate cyclase inhibitor activity IEA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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