ENSG00000173227


Homo sapiens

Features
Gene ID: ENSG00000173227
  
Biological name :SYT12
  
Synonyms : Q8IV01 / synaptotagmin 12 / SYT12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 67006778
Gene end: 67050863
  
Corresponding Affymetrix probe sets: 215860_at (Human Genome U133 Plus 2.0 Array)   215865_at (Human Genome U133 Plus 2.0 Array)   228072_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435316
Ensembl peptide - ENSP00000377520
Ensembl peptide - ENSP00000431400
Ensembl peptide - ENSP00000434709
NCBI entrez gene - 91683     See in Manteia.
OMIM - 606436
RefSeq - XM_017018548
RefSeq - NM_001177880
RefSeq - NM_001318773
RefSeq - NM_001318775
RefSeq - NM_177963
RefSeq - XM_006718737
RefSeq - XM_011545346
RefSeq - XM_011545347
RefSeq - XM_017018547
RefSeq Peptide - NP_001171351
RefSeq Peptide - NP_001305702
RefSeq Peptide - NP_001305704
RefSeq Peptide - NP_808878
swissprot - Q8IV01
swissprot - E9PNM5
Ensembl - ENSG00000173227
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt12ENSDARG00000101776Danio rerio
 SYT12ENSGALG00000004306Gallus gallus
 Syt12ENSMUSG00000049303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT17 / Q9BSW7 / synaptotagmin 17ENSG0000010352828
SYT13 / Q7L8C5 / synaptotagmin 13ENSG0000001950524
FO681492.1ENSG0000027775823
SYT15 / Q9BQS2 / synaptotagmin 15ENSG0000020417623
SYT14 / Q8NB59 / synaptotagmin 14ENSG0000014346921
SYT16 / Q17RD7 / synaptotagmin 16ENSG0000013997321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR030537  Synaptotagmin-12
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0046928 regulation of neurotransmitter secretion IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0048792 spontaneous exocytosis of neurotransmitter IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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