ENSG00000173598


Homo sapiens

Features
Gene ID: ENSG00000173598
  
Biological name :NUDT4
  
Synonyms : nudix hydrolase 4 / NUDT4 / Q9NZJ9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q22
Gene start: 93377883
Gene end: 93408146
  
Corresponding Affymetrix probe sets: 206302_s_at (Human Genome U133 Plus 2.0 Array)   206303_s_at (Human Genome U133 Plus 2.0 Array)   212181_s_at (Human Genome U133 Plus 2.0 Array)   212182_at (Human Genome U133 Plus 2.0 Array)   212183_at (Human Genome U133 Plus 2.0 Array)   227683_x_at (Human Genome U133 Plus 2.0 Array)   229836_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448504
Ensembl peptide - ENSP00000406612
Ensembl peptide - ENSP00000448032
Ensembl peptide - ENSP00000448620
Ensembl peptide - ENSP00000449724
Ensembl peptide - ENSP00000449552
Ensembl peptide - ENSP00000338352
NCBI entrez gene - 440672     See in Manteia.
NCBI entrez gene - 11163     See in Manteia.
OMIM - 609229
RefSeq - XM_011537796
RefSeq - NM_001301022
RefSeq - NM_001301023
RefSeq - NM_001301024
RefSeq - NM_019094
RefSeq - NM_199040
RefSeq - XM_011537794
RefSeq - XM_011537795
RefSeq Peptide - NP_001287952
RefSeq Peptide - NP_001287953
RefSeq Peptide - NP_001287951
RefSeq Peptide - NP_001342336
RefSeq Peptide - NP_061967
RefSeq Peptide - NP_950241
swissprot - A0A024RBG1
swissprot - A0A024RBD0
swissprot - A0A0C4DGJ4
swissprot - Q9NZJ9
swissprot - F8VRL4
swissprot - F8VRR0
Ensembl - ENSG00000173598
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011285Gallus gallus
 Nudt4ENSMUSG00000020029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUDT4B / nudix hydrolase 4BENSG00000177144100
NUDT11 / Q96G61 / nudix hydrolase 11ENSG0000019636882
NUDT10 / Q8NFP7 / nudix hydrolase 10ENSG0000012282481
NUDT3 / O95989 / nudix hydrolase 3ENSG0000027232571


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009187 cyclic nucleotide metabolic process TAS
 biological_processGO:0019722 calcium-mediated signaling TAS
 biological_processGO:0019935 cyclic-nucleotide-mediated signaling TAS
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 biological_processGO:0046831 regulation of RNA export from nucleus TAS
 biological_processGO:0046907 intracellular transport TAS
 biological_processGO:0071543 diphosphoinositol polyphosphate metabolic process IBA
 biological_processGO:1901907 diadenosine pentaphosphate catabolic process IBA
 biological_processGO:1901909 diadenosine hexaphosphate catabolic process IBA
 biological_processGO:1901911 adenosine 5"-(hexahydrogen pentaphosphate) catabolic process IBA
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000298 endopolyphosphatase activity IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008486 diphosphoinositol-polyphosphate diphosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030515 snoRNA binding ISS
 molecular_functionGO:0034431 bis(5"-adenosyl)-hexaphosphatase activity IBA
 molecular_functionGO:0034432 bis(5"-adenosyl)-pentaphosphatase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity IBA
 molecular_functionGO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity TAS
 molecular_functionGO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity TAS
 molecular_functionGO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity TAS
 molecular_functionGO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity IEA
 molecular_functionGO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA
 molecular_functionGO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr