ENSG00000272325


Homo sapiens

Features
Gene ID: ENSG00000272325
  
Biological name :NUDT3
  
Synonyms : nudix hydrolase 3 / NUDT3 / O95989
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.31
Gene start: 34279679
Gene end: 34392674
  
Corresponding Affymetrix probe sets: 1569990_at (Human Genome U133 Plus 2.0 Array)   211973_at (Human Genome U133 Plus 2.0 Array)   211976_at (Human Genome U133 Plus 2.0 Array)   212605_s_at (Human Genome U133 Plus 2.0 Array)   212608_s_at (Human Genome U133 Plus 2.0 Array)   221579_s_at (Human Genome U133 Plus 2.0 Array)   229803_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476119
NCBI entrez gene - 11165     See in Manteia.
OMIM - 609228
RefSeq - NM_006703
RefSeq Peptide - NP_006694
swissprot - O95989
Ensembl - ENSG00000272325
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt3aENSDARG00000016256Danio rerio
 nudt3bENSDARG00000042123Danio rerio
 NUDT3ENSGALG00000002830Gallus gallus
 Nudt3ENSMUSG00000024213Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUDT4 / Q9NZJ9 / nudix hydrolase 4ENSG0000017359874
NUDT4B / nudix hydrolase 4BENSG0000017714474
NUDT10 / Q8NFP7 / nudix hydrolase 10ENSG0000012282472
NUDT11 / Q96G61 / nudix hydrolase 11ENSG0000019636872


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0015961 diadenosine polyphosphate catabolic process TAS
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 biological_processGO:0071544 diphosphoinositol polyphosphate catabolic process IDA
 biological_processGO:1901907 diadenosine pentaphosphate catabolic process IBA
 biological_processGO:1901909 diadenosine hexaphosphate catabolic process IBA
 biological_processGO:1901911 adenosine 5"-(hexahydrogen pentaphosphate) catabolic process IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0000298 endopolyphosphatase activity IBA
 molecular_functionGO:0008486 diphosphoinositol-polyphosphate diphosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034431 bis(5"-adenosyl)-hexaphosphatase activity IBA
 molecular_functionGO:0034432 bis(5"-adenosyl)-pentaphosphatase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity IBA
 molecular_functionGO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity TAS
 molecular_functionGO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity TAS
 molecular_functionGO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity IEA
 molecular_functionGO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA
 molecular_functionGO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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