ENSG00000173706


Homo sapiens

Features
Gene ID: ENSG00000173706
  
Biological name :HEG1
  
Synonyms : heart development protein with EGF like domains 1 / HEG1 / Q9ULI3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q21.2
Gene start: 124965710
Gene end: 125055958
  
Corresponding Affymetrix probe sets: 212822_at (Human Genome U133 Plus 2.0 Array)   213069_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311502
Ensembl peptide - ENSP00000417494
Ensembl peptide - ENSP00000417648
Ensembl peptide - ENSP00000494391
NCBI entrez gene - 57493     See in Manteia.
OMIM - 614182
RefSeq - XM_005247666
RefSeq - NM_020733
RefSeq Peptide - NP_065784
swissprot - H7C4K2
swissprot - Q9ULI3
swissprot - H7C4M4
Ensembl - ENSG00000173706
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 heg1ENSDARG00000018441Danio rerio
 HEG1ENSGALG00000011813Gallus gallus
 1 ENSMUSG00000075254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR028720  Protein HEG


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001885 endothelial cell development IEA
 biological_processGO:0001886 endothelial cell morphogenesis IEA
 biological_processGO:0001944 vasculature development IEA
 biological_processGO:0001945 lymph vessel development IEA
 biological_processGO:0003017 lymph circulation IEA
 biological_processGO:0003209 cardiac atrium morphogenesis IEA
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IEA
 biological_processGO:0003281 ventricular septum development IEA
 biological_processGO:0007043 cell-cell junction assembly IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0045216 cell-cell junction organization IEA
 biological_processGO:0048845 venous blood vessel morphogenesis IEA
 biological_processGO:0050878 regulation of body fluid levels IEA
 biological_processGO:0055017 cardiac muscle tissue growth IEA
 biological_processGO:0060039 pericardium development IEA
 biological_processGO:0090271 positive regulation of fibroblast growth factor production IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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