ENSG00000176393


Homo sapiens

Features
Gene ID: ENSG00000176393
  
Biological name :RNPEP
  
Synonyms : arginyl aminopeptidase / Q9H4A4 / RNPEP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 201982372
Gene end: 202006147
  
Corresponding Affymetrix probe sets: 201003_x_at (Human Genome U133 Plus 2.0 Array)   208270_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356255
Ensembl peptide - ENSP00000295640
Ensembl peptide - ENSP00000389602
Ensembl peptide - ENSP00000478884
Ensembl peptide - ENSP00000478325
Ensembl peptide - ENSP00000407614
NCBI entrez gene - 6051     See in Manteia.
OMIM - 602675
RefSeq - XM_017002022
RefSeq - NM_001319182
RefSeq - NM_001319183
RefSeq - NM_001319184
RefSeq - NM_020216
RefSeq - XM_005245421
RefSeq Peptide - NP_064601
RefSeq Peptide - NP_001306111
RefSeq Peptide - NP_001306112
RefSeq Peptide - NP_001306113
swissprot - H7C2T3
swissprot - C9JMZ3
swissprot - A6NKB8
swissprot - Q9H4A4
swissprot - A0A087WU27
swissprot - A0A087WUS4
Ensembl - ENSG00000176393
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnpepENSDARG00000012506Danio rerio
 RNPEPENSGALG00000000374Gallus gallus
 RnpepENSMUSG00000041926Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HAU8 / RNPEPL1 / arginyl aminopeptidase like 1ENSG0000014232747
LTA4H / P09960 / leukotriene A4 hydrolaseENSG0000011114435
C9orf3 / Q8N6M6 / chromosome 9 open reading frame 3ENSG0000014812025


Protein motifs (from Interpro)
Interpro ID Name
 IPR001930  Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
 IPR014782  Peptidase M1, membrane alanine aminopeptidase, N-terminal
 IPR015211  Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal
 IPR015571  Peptidase M1, aminopeptidase B
 IPR016024  Armadillo-type fold
 IPR034015  Leukotriene A4 hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043171 peptide catabolic process IBA
 biological_processGO:0045776 negative regulation of blood pressure IBA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0030141 secretory granule IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004177 aminopeptidase activity IEA
 molecular_functionGO:0004301 epoxide hydrolase activity NAS
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity NAS
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042277 peptide binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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