ENSG00000176406


Homo sapiens

Features
Gene ID: ENSG00000176406
  
Biological name :RIMS2
  
Synonyms : Q9UQ26 / regulating synaptic membrane exocytosis 2 / RIMS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q22.3
Gene start: 103500748
Gene end: 104256094
  
Corresponding Affymetrix probe sets: 206137_at (Human Genome U133 Plus 2.0 Array)   209134_s_at (Human Genome U133 Plus 2.0 Array)   215478_at (Human Genome U133 Plus 2.0 Array)   229823_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423559
Ensembl peptide - ENSP00000390665
Ensembl peptide - ENSP00000425205
Ensembl peptide - ENSP00000488393
Ensembl peptide - ENSP00000487907
Ensembl peptide - ENSP00000428478
Ensembl peptide - ENSP00000427018
Ensembl peptide - ENSP00000262231
Ensembl peptide - ENSP00000342051
Ensembl peptide - ENSP00000386228
NCBI entrez gene - 9699     See in Manteia.
OMIM - 606630
RefSeq - XM_017014046
RefSeq - XM_017014035
RefSeq - XM_017014036
RefSeq - XM_017014037
RefSeq - XM_017014038
RefSeq - XM_017014039
RefSeq - XM_017014040
RefSeq - XM_017014041
RefSeq - XM_017014042
RefSeq - XM_017014043
RefSeq - XM_017014044
RefSeq - XM_017014045
RefSeq - NM_001100117
RefSeq - NM_001282881
RefSeq - NM_001282882
RefSeq - NM_014677
RefSeq - XM_005251106
RefSeq - XM_005251107
RefSeq - XM_006716698
RefSeq - XM_011517395
RefSeq - XM_011517398
RefSeq - XM_017014006
RefSeq - XM_017014007
RefSeq - XM_017014008
RefSeq - XM_017014009
RefSeq - XM_017014010
RefSeq - XM_017014011
RefSeq - XM_017014012
RefSeq - XM_017014013
RefSeq - XM_017014014
RefSeq - XM_017014015
RefSeq - XM_017014016
RefSeq - XM_017014017
RefSeq - XM_017014018
RefSeq - XM_017014019
RefSeq - XM_017014020
RefSeq - XM_017014021
RefSeq - XM_017014022
RefSeq - XM_017014023
RefSeq - XM_017014024
RefSeq - XM_017014025
RefSeq - XM_017014026
RefSeq - XM_017014027
RefSeq - XM_017014028
RefSeq - XM_017014029
RefSeq - XM_017014030
RefSeq - XM_017014031
RefSeq - XM_017014032
RefSeq - XM_017014033
RefSeq - XM_017014034
RefSeq Peptide - NP_001269810
RefSeq Peptide - NP_001269811
RefSeq Peptide - NP_055492
RefSeq Peptide - NP_001093587
swissprot - F8W6W8
swissprot - A0A0J9YWD4
swissprot - E5RI36
swissprot - Q9UQ26
swissprot - D6RDY0
swissprot - D6RA03
swissprot - A0A0J9YXG4
Ensembl - ENSG00000176406
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rims2aENSDARG00000101606Danio rerio
 rims2bENSDARG00000102690Danio rerio
 RIMS2ENSGALG00000040256Gallus gallus
 Rims2ENSMUSG00000037386Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RIMS1 / Q86UR5 / regulating synaptic membrane exocytosis 1ENSG0000007984163
RIMS3 / Q9UJD0 / regulating synaptic membrane exocytosis 3ENSG0000011701613
RIMS4 / Q9H426 / regulating synaptic membrane exocytosis 4ENSG0000010109812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001478  PDZ domain
 IPR010911  Rab-binding domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR030631  Regulating synaptic membrane exocytosis protein 2
 IPR035892  C2 domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0017156 calcium ion regulated exocytosis ISS
 biological_processGO:0017157 regulation of exocytosis ISS
 biological_processGO:0019933 cAMP-mediated signaling ISS
 biological_processGO:0030073 insulin secretion ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042391 regulation of membrane potential ISS
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter ISS
 biological_processGO:0061669 spontaneous neurotransmitter secretion ISS
 biological_processGO:0097151 positive regulation of inhibitory postsynaptic potential ISS
 biological_processGO:1903861 positive regulation of dendrite extension IDA
 biological_processGO:2000300 regulation of synaptic vesicle exocytosis IBA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048786 presynaptic active zone TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0044325 ion channel binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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