ENSG00000177414


Homo sapiens

Features
Gene ID: ENSG00000177414
  
Biological name :UBE2U
  
Synonyms : Q5VVX9 / UBE2U / ubiquitin conjugating enzyme E2 U (putative)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.3
Gene start: 64203627
Gene end: 64267368
  
Corresponding Affymetrix probe sets: 1553776_at (Human Genome U133 Plus 2.0 Array)   242392_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477356
Ensembl peptide - ENSP00000481174
Ensembl peptide - ENSP00000360116
Ensembl peptide - ENSP00000360117
Ensembl peptide - ENSP00000476556
NCBI entrez gene - 148581     See in Manteia.
RefSeq - XM_017000385
RefSeq - XM_017000379
RefSeq - XM_017000380
RefSeq - XM_017000381
RefSeq - XM_017000382
RefSeq - XM_017000383
RefSeq - XM_017000384
RefSeq - NM_152489
RefSeq - XM_005270498
RefSeq - XM_006710379
RefSeq - XM_011540764
RefSeq Peptide - NP_689702
swissprot - A0A140VJY9
swissprot - A0A0A0MRP4
swissprot - Q5VVX9
swissprot - V9GYA6
swissprot - V9GZ31
Ensembl - ENSG00000177414
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ube2uENSMUSG00000069733Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2A / P49459 / ubiquitin conjugating enzyme E2 AENSG0000007772121
UBE2B / P63146 / ubiquitin conjugating enzyme E2 BENSG0000011904820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0016574 histone ubiquitination IBA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0033503 HULC complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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