ENSG00000177425


Homo sapiens

Features
Gene ID: ENSG00000177425
  
Biological name :PAWR
  
Synonyms : PAWR / pro-apoptotic WT1 regulator / Q96IZ0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q21.2
Gene start: 79574979
Gene end: 79691097
  
Corresponding Affymetrix probe sets: 204004_at (Human Genome U133 Plus 2.0 Array)   204005_s_at (Human Genome U133 Plus 2.0 Array)   214090_at (Human Genome U133 Plus 2.0 Array)   214237_x_at (Human Genome U133 Plus 2.0 Array)   226223_at (Human Genome U133 Plus 2.0 Array)   226231_at (Human Genome U133 Plus 2.0 Array)   229515_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328088
Ensembl peptide - ENSP00000447507
Ensembl peptide - ENSP00000448317
Ensembl peptide - ENSP00000449928
Ensembl peptide - ENSP00000447454
NCBI entrez gene - 5074     See in Manteia.
OMIM - 601936
RefSeq - XM_017019377
RefSeq - NM_001354732
RefSeq - NM_002583
RefSeq - XM_006719435
RefSeq - XM_006719436
RefSeq Peptide - NP_001341661
RefSeq Peptide - NP_002574
swissprot - H0YHP5
swissprot - H0YI16
swissprot - Q96IZ0
swissprot - F8W1M8
swissprot - A0A0B4J260
Ensembl - ENSG00000177425
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pawrENSDARG00000045486Danio rerio
 PAWRENSGALG00000010320Gallus gallus
 PawrENSMUSG00000035873Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026117  Prostate apoptosis response 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030889 negative regulation of B cell proliferation IEA
 biological_processGO:0042094 interleukin-2 biosynthetic process IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0042986 positive regulation of amyloid precursor protein biosynthetic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IBA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IEA
 biological_processGO:0051017 actin filament bundle assembly ISS
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death IEA
 biological_processGO:2000774 positive regulation of cellular senescence IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005884 actin filament IBA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IDA
 molecular_functionGO:0043522 leucine zipper domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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