ENSG00000177981


Homo sapiens

Features
Gene ID: ENSG00000177981
  
Biological name :ASB8
  
Synonyms : ankyrin repeat and SOCS box containing 8 / ASB8 / Q9H765
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.11
Gene start: 48147788
Gene end: 48181213
  
Corresponding Affymetrix probe sets: 218841_at (Human Genome U133 Plus 2.0 Array)   226861_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486138
Ensembl peptide - ENSP00000445622
Ensembl peptide - ENSP00000447819
Ensembl peptide - ENSP00000320893
Ensembl peptide - ENSP00000437530
Ensembl peptide - ENSP00000437769
Ensembl peptide - ENSP00000438434
Ensembl peptide - ENSP00000438498
Ensembl peptide - ENSP00000439557
Ensembl peptide - ENSP00000440773
Ensembl peptide - ENSP00000442639
Ensembl peptide - ENSP00000442737
Ensembl peptide - ENSP00000443148
Ensembl peptide - ENSP00000443835
Ensembl peptide - ENSP00000444093
Ensembl peptide - ENSP00000445540
NCBI entrez gene - 140461     See in Manteia.
OMIM - 615053
RefSeq - NM_001319297
RefSeq - NM_024095
RefSeq - NM_001319301
RefSeq - NM_001319300
RefSeq - NM_001319299
RefSeq - NM_001319298
RefSeq - NM_001319296
RefSeq Peptide - NP_001306227
RefSeq Peptide - NP_001306225
RefSeq Peptide - NP_001306226
RefSeq Peptide - NP_001306228
RefSeq Peptide - NP_001306229
RefSeq Peptide - NP_001306230
RefSeq Peptide - NP_077000
swissprot - F5H023
swissprot - F5GZZ3
swissprot - F5GYF0
swissprot - Q9H765
swissprot - F8VS92
swissprot - F5H7B4
swissprot - F5H772
swissprot - F5H6A7
swissprot - F5H5S9
swissprot - F5H243
Ensembl - ENSG00000177981
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asb8ENSDARG00000003383Danio rerio
 Asb8ENSMUSG00000048175Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANKEF1 / Q9NU02 / ankyrin repeat and EF-hand domain containing 1ENSG0000013262325
O75832 / PSMD10 / proteasome 26S subunit, non-ATPase 10ENSG0000010184322
Q86SG2 / ANKRD23 / ankyrin repeat domain 23ENSG0000016312621
ANKRD2 / Q9GZV1 / ankyrin repeat domain 2ENSG0000016588718
ANKRD1 / Q15327 / ankyrin repeat domain 1ENSG0000014867718
Q6NXT1 / ANKRD54 / ankyrin repeat domain 54ENSG0000010012415


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036036  SOCS box-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037332  Ankyrin repeat and SOCS box protein 8, SOCS box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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