ENSG00000180447


Homo sapiens

Features
Gene ID: ENSG00000180447
  
Biological name :GAS1
  
Synonyms : GAS1 / growth arrest specific 1 / P54826
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q21.33
Gene start: 86944363
Gene end: 86947189
  
Corresponding Affymetrix probe sets: 204456_s_at (Human Genome U133 Plus 2.0 Array)   204457_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298743
NCBI entrez gene - 2619     See in Manteia.
OMIM - 139185
RefSeq - NM_002048
RefSeq Peptide - NP_002039
swissprot - P54826
Ensembl - ENSG00000180447
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gas1aENSDARG00000077298Danio rerio
 gas1bENSDARG00000067984Danio rerio
 GAS1ENSGALG00000017658Gallus gallus
 Gas1ENSMUSG00000052957Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016017  GDNF/GAS1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0008589 regulation of smoothened signaling pathway ISS
 biological_processGO:0010955 negative regulation of protein processing IMP
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IEP
 biological_processGO:0042981 regulation of apoptotic process ISS
 biological_processGO:0045165 cell fate commitment ISS
 biological_processGO:0045930 negative regulation of mitotic cell cycle IGI
 biological_processGO:0048589 developmental growth ISS
 biological_processGO:0060628 regulation of ER to Golgi vesicle-mediated transport IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane ISS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Ligand-receptor interactions
Activation of SMO


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164690 SHH / Q15465 / sonic hedgehog  / reaction / complex
 ENSG00000185920 PTCH1 / Q13635 / patched 1  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr