ENSG00000181143


Homo sapiens

Features
Gene ID: ENSG00000181143
  
Biological name :MUC16
  
Synonyms : MUC16 / mucin 16, cell surface associated / Q8WXI7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 8848844
Gene end: 8981342
  
Corresponding Affymetrix probe sets: 220196_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381008
Ensembl peptide - ENSP00000470885
Ensembl peptide - ENSP00000472781
Ensembl peptide - ENSP00000472883
NCBI entrez gene - 94025     See in Manteia.
OMIM - 606154
RefSeq - XM_017027501
RefSeq - XM_017027494
RefSeq - XM_017027495
RefSeq - XM_017027496
RefSeq - XM_017027499
RefSeq - XM_017027500
RefSeq - NM_024690
RefSeq - XM_017027486
RefSeq - XM_017027487
RefSeq - XM_017027488
RefSeq - XM_017027489
RefSeq - XM_017027490
RefSeq - XM_017027491
RefSeq - XM_017027492
RefSeq - XM_017027493
RefSeq Peptide - NP_078966
swissprot - M0R2S7
swissprot - M0R2Y5
swissprot - M0QZZ9
swissprot - Q8WXI7
Ensembl - ENSG00000181143
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Muc16ENSMUSG00000109564Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR028850  Mucin-16
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0016266 O-glycan processing TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Dectin-2 family
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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