ENSMUSG00000109564


Mus musculus

Features
Gene ID: ENSMUSG00000109564
  
Biological name :Muc16
  
Synonyms : Muc16
  
Possible biological names infered from orthology : mucin 16, cell surface associated / Q8WXI7
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A2
Gene start: 18495455
Gene end: 18674530
  
Corresponding Affymetrix probe sets: 10591169 (MoGene1.0st)   1432358_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034653
Ensembl peptide - ENSMUSP00000147104
Ensembl peptide - ENSMUSP00000146740
Ensembl peptide - ENSMUSP00000146623
NCBI entrez gene - 73732     See in Manteia.
MGI - MGI:1920982
RefSeq - XM_011242634
RefSeq - XM_011242635
RefSeq - XM_011242636
swissprot - Q9D1H1
swissprot - A0A140LIA5
swissprot - A0A140LI05
swissprot - A0A140LJ72
Ensembl - ENSMUSG00000109564
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MUC16ENSG00000181143Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR028850  Mucin-16
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045409 negative regulation of interleukin-6 biosynthetic process IMP
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IMP
 biological_processGO:0061045 negative regulation of wound healing IMP
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001934 increased litter size "greater numbers of live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxd12tm2Ddu/Hoxd12tm2Ddu,Hoxd13tm2Ddu/Hoxd13tm2Ddu
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr