ENSG00000181220


Homo sapiens

Features
Gene ID: ENSG00000181220
  
Biological name :ZNF746
  
Synonyms : Q6NUN9 / zinc finger protein 746 / ZNF746
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q36.1
Gene start: 149472696
Gene end: 149497817
  
Corresponding Affymetrix probe sets: 1570373_at (Human Genome U133 Plus 2.0 Array)   225848_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000493970
Ensembl peptide - ENSP00000345140
Ensembl peptide - ENSP00000395007
Ensembl peptide - ENSP00000420329
NCBI entrez gene - 155061     See in Manteia.
OMIM - 613914
RefSeq - XM_011515838
RefSeq - NM_001163474
RefSeq - NM_152557
RefSeq - XM_005249955
RefSeq - XM_005249956
RefSeq - XM_005249957
RefSeq Peptide - NP_001156946
RefSeq Peptide - NP_689770
swissprot - C9JNZ9
swissprot - Q6NUN9
Ensembl - ENSG00000181220
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044098Gallus gallus
 Q3U133ENSMUSG00000057691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZMS7 / ZNF783 / zinc finger family member 783ENSG0000020494636
Q8TD17 / ZNF398 / zinc finger protein 398ENSG0000019702434
Q9UDV7 / ZNF282 / zinc finger protein 282ENSG0000017026533
Q9ULD5 / ZNF777 / zinc finger protein 777ENSG0000019645332
Q9UDV6 / ZNF212 / zinc finger protein 212ENSG0000017026029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR022137  Protein of unknown function DUF3669, zinc finger protein
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:1901216 positive regulation of neuron death IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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