ENSG00000181754


Homo sapiens

Features
Gene ID: ENSG00000181754
  
Biological name :AMIGO1
  
Synonyms : adhesion molecule with Ig like domain 1 / AMIGO1 / Q86WK6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.3
Gene start: 109504175
Gene end: 109509738
  
Corresponding Affymetrix probe sets: 226718_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358878
Ensembl peptide - ENSP00000358880
NCBI entrez gene - 57463     See in Manteia.
OMIM - 615689
RefSeq - XM_011541812
RefSeq - NM_020703
RefSeq Peptide - NP_065754
swissprot - Q86WK6
Ensembl - ENSG00000181754
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amigo1ENSDARG00000079620Danio rerio
 Amigo1ENSMUSG00000050947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMIGO2 / Q86SJ2 / adhesion molecule with Ig like domain 2ENSG0000013921140
AMIGO3 / Q86WK7 / adhesion molecule with Ig like domain 3ENSG0000017602037


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR031283  Amphoterin-induced protein
 IPR031284  Amphoterin-induced protein 1
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules ISS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0007413 axonal fasciculation ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042552 myelination ISS
 biological_processGO:0050772 positive regulation of axonogenesis ISS
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1901381 positive regulation of potassium ion transmembrane transport ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0032809 neuronal cell body membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015459 potassium channel regulator activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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