ENSG00000182149


Homo sapiens

Features
Gene ID: ENSG00000182149
  
Biological name :IST1
  
Synonyms : IST1 / IST1, ESCRT-III associated factor / P53990
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.2
Gene start: 71845996
Gene end: 71931199
  
Corresponding Affymetrix probe sets: 1562848_at (Human Genome U133 Plus 2.0 Array)   200851_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454541
Ensembl peptide - ENSP00000330408
Ensembl peptide - ENSP00000368075
Ensembl peptide - ENSP00000368076
Ensembl peptide - ENSP00000398505
Ensembl peptide - ENSP00000410081
Ensembl peptide - ENSP00000414942
Ensembl peptide - ENSP00000438399
Ensembl peptide - ENSP00000455409
Ensembl peptide - ENSP00000455590
Ensembl peptide - ENSP00000455757
Ensembl peptide - ENSP00000455805
Ensembl peptide - ENSP00000455860
Ensembl peptide - ENSP00000456200
Ensembl peptide - ENSP00000457646
Ensembl peptide - ENSP00000457844
Ensembl peptide - ENSP00000463711
Ensembl peptide - ENSP00000463833
Ensembl peptide - ENSP00000475853
Ensembl peptide - ENSP00000486751
NCBI entrez gene - 9798     See in Manteia.
OMIM - 616434
RefSeq - NM_014761
RefSeq - NM_001270979
RefSeq - NM_001270978
RefSeq - NM_001270977
RefSeq - NM_001270976
RefSeq - NM_001270975
RefSeq Peptide - NP_001257908
RefSeq Peptide - NP_055576
RefSeq Peptide - NP_001257904
RefSeq Peptide - NP_001257905
RefSeq Peptide - NP_001257906
RefSeq Peptide - NP_001257907
swissprot - H3BQF7
swissprot - H3BQ38
swissprot - E9PF00
swissprot - H3BPP6
swissprot - H3BMU1
swissprot - F5GXM3
swissprot - P53990
swissprot - H3BRE2
swissprot - H3BUI0
swissprot - J3KR23
swissprot - J3QQP8
Ensembl - ENSG00000182149
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ist1ENSDARG00000051888Danio rerio
 IST1ENSGALG00000000811Gallus gallus
 Ist1ENSMUSG00000031729Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005061  Vacuolar protein sorting-associated protein Ist1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008104 protein localization IMP
 biological_processGO:0009838 abscission IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019076 viral release from host cell IDA
 biological_processGO:0036258 multivesicular body assembly NAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045184 establishment of protein localization IMP
 biological_processGO:0045862 positive regulation of proteolysis IDA
 biological_processGO:0046745 viral capsid secondary envelopment IDA
 biological_processGO:0048672 positive regulation of collateral sprouting IEA
 biological_processGO:0051301 cell division IMP
 biological_processGO:0061640 cytoskeleton-dependent cytokinesis IMP
 biological_processGO:1904903 ESCRT III complex disassembly NAS
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0090543 Flemming body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0090541 MIT domain binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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