ENSG00000183317


Homo sapiens

Features
Gene ID: ENSG00000183317
  
Biological name :EPHA10
  
Synonyms : EPHA10 / EPH receptor A10 / Q5JZY3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 37713880
Gene end: 37765133
  
Corresponding Affymetrix probe sets: 1553371_at (Human Genome U133 Plus 2.0 Array)   236073_at (Human Genome U133 Plus 2.0 Array)   243717_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441822
Ensembl peptide - ENSP00000436288
Ensembl peptide - ENSP00000436425
Ensembl peptide - ENSP00000316395
Ensembl peptide - ENSP00000362139
Ensembl peptide - ENSP00000397746
Ensembl peptide - ENSP00000431389
Ensembl peptide - ENSP00000432693
NCBI entrez gene - 284656     See in Manteia.
OMIM - 611123
RefSeq - XM_017001080
RefSeq - NM_001099439
RefSeq - NM_173641
RefSeq Peptide - NP_001092909
RefSeq Peptide - NP_775912
swissprot - J3KQG3
swissprot - Q5JZY3
swissprot - F5GWI2
swissprot - H0YCC9
swissprot - H0YEP6
swissprot - H0YD12
swissprot - H0YER4
Ensembl - ENSG00000183317
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01071972.1ENSDARG00000075321Danio rerio
 ENSGALG00000044149Gallus gallus
 ENSGALG00000001912Gallus gallus
 Epha10ENSMUSG00000028876Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPHA2 / P29317 / EPH receptor A2ENSG0000014262740


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR027936  Ephrin receptor, transmembrane domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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