ENSMUSG00000028876


Mus musculus

Features
Gene ID: ENSMUSG00000028876
  
Biological name :Epha10
  
Synonyms : Epha10 / Ephrin type-A receptor 10 / Q8BYG9
  
Possible biological names infered from orthology : EPH receptor A10 / Q5JZY3
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.2
Gene start: 124880899
Gene end: 124917800
  
Corresponding Affymetrix probe sets: 10507983 (MoGene1.0st)   10507990 (MoGene1.0st)   1436093_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050810
Ensembl peptide - ENSMUSP00000118801
NCBI entrez gene - 230735     See in Manteia.
MGI - MGI:3586824
RefSeq - XM_017320152
RefSeq - NM_001256432
RefSeq - NM_177671
RefSeq Peptide - NP_001243361
RefSeq Peptide - NP_808339
swissprot - Q8BYG9
swissprot - F6WVB0
Ensembl - ENSMUSG00000028876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01071972.1ENSDARG00000075321Danio rerio
 ENSGALG00000044149Gallus gallus
 ENSGALG00000001912Gallus gallus
 EPHA10ENSG00000183317Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR027936  Ephrin receptor, transmembrane domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005005 transmembrane-ephrin receptor activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Epb41tm1b(KOMP)Mbp/Epb41+
Genetic Background: C57BL/6N-Epb41tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr