ENSG00000183479


Homo sapiens

Features
Gene ID: ENSG00000183479
  
Biological name :TREX2
  
Synonyms : Q9BQ50 / three prime repair exonuclease 2 / TREX2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q28
Gene start: 153444720
Gene end: 153470587
  
Corresponding Affymetrix probe sets: 207891_s_at (Human Genome U133 Plus 2.0 Array)   211788_s_at (Human Genome U133 Plus 2.0 Array)   213334_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359252
Ensembl peptide - ENSP00000377442
Ensembl peptide - ENSP00000333441
Ensembl peptide - ENSP00000334993
Ensembl peptide - ENSP00000345218
Ensembl peptide - ENSP00000359231
Ensembl peptide - ENSP00000359251
NCBI entrez gene - 11219     See in Manteia.
OMIM - 300370
RefSeq - NM_080701
RefSeq Peptide - NP_542432
swissprot - Q9BQ50
Ensembl - ENSG00000183479
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Trex2ENSMUSG00000031372Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TREX1 / Q9NSU2 / three prime repair exonuclease 1ENSG0000021368945


Protein motifs (from Interpro)
Interpro ID Name
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR034926  Three prime repair exonuclease 2
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IDA
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0008296 3"-5"-exodeoxyribonuclease activity IDA
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA
 molecular_functionGO:0008853 exodeoxyribonuclease III activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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