ENSG00000183733


Homo sapiens

Features
Gene ID: ENSG00000183733
  
Biological name :FIGLA
  
Synonyms : FIGLA / folliculogenesis specific bHLH transcription factor / Q6QHK4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p13.3
Gene start: 70777310
Gene end: 70790643
  
Corresponding Affymetrix probe sets: 1570337_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333097
NCBI entrez gene - 344018     See in Manteia.
OMIM - 608697
RefSeq - NM_001004311
RefSeq Peptide - NP_001004311
swissprot - Q6QHK4
Ensembl - ENSG00000183733
  
Related genetic diseases (OMIM): 612310 - Premature ovarian failure 6, 612310

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 figlaENSDARG00000087166Danio rerio
 FiglaENSMUSG00000030001Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048477 oogenesis IEA
 biological_processGO:0048599 oocyte development NAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000013 Hypoplastic uterus 
Show

 HP:0001470 Sex-limited autosomal dominant 
Show

 HP:0008209 Premature ovarian failure 
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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