ENSG00000183943


Homo sapiens

Features
Gene ID: ENSG00000183943
  
Biological name :PRKX
  
Synonyms : P51817 / PRKX / protein kinase, X-linked
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.33
Gene start: 3604370
Gene end: 3713608
  
Corresponding Affymetrix probe sets: 204060_s_at (Human Genome U133 Plus 2.0 Array)   204061_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262848
NCBI entrez gene - 5613     See in Manteia.
OMIM - 300083
RefSeq - NM_005044
RefSeq Peptide - NP_005035
swissprot - A0A024RBU5
swissprot - P51817
Ensembl - ENSG00000183943
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkxENSDARG00000060716Danio rerio
 PRKXENSGALG00000042759Gallus gallus
 PrkxENSMUSG00000035725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P22694 / PRKACB / protein kinase cAMP-activated catalytic subunit betaENSG0000014287548
P17612 / PRKACA / protein kinase cAMP-activated catalytic subunit alphaENSG0000007206247
P22612 / PRKACG / protein kinase cAMP-activated catalytic subunit gammaENSG0000016505943
PRKG1 / Q13976 / protein kinase, cGMP-dependent, type IENSG0000018553241
PRKG2 / Q13237 / protein kinase, cGMP-dependent, type IIENSG0000013866941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001935 endothelial cell proliferation IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0030099 myeloid cell differentiation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030155 regulation of cell adhesion IDA
 biological_processGO:0030334 regulation of cell migration IDA
 biological_processGO:0031589 cell-substrate adhesion IMP
 biological_processGO:0043542 endothelial cell migration IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0060562 epithelial tube morphogenesis IDA
 biological_processGO:0060993 kidney morphogenesis IDA
 biological_processGO:2000696 regulation of epithelial cell differentiation involved in kidney development IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004691 cAMP-dependent protein kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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