ENSG00000184261


Homo sapiens

Features
Gene ID: ENSG00000184261
  
Biological name :KCNK12
  
Synonyms : KCNK12 / potassium two pore domain channel subfamily K member 12 / Q9HB15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p16.3
Gene start: 47516581
Gene end: 47570939
  
Corresponding Affymetrix probe sets: 220448_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327611
NCBI entrez gene - 56660     See in Manteia.
OMIM - 607366
RefSeq - NM_022055
RefSeq Peptide - NP_071338
swissprot - Q9HB15
Ensembl - ENSG00000184261
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNK12ENSDARG00000074530Danio rerio
 KCNK12ENSGALG00000008960Gallus gallus
 Kcnk12ENSMUSG00000050138Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNK13 / Q9HB14 / potassium two pore domain channel subfamily K member 13ENSG0000015231560


Protein motifs (from Interpro)
Interpro ID Name
 IPR003280  Two pore domain potassium channel
 IPR005410  Two pore domain potassium channel, THIK
 IPR013099  Potassium channel domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000184261 KCNK12 / Q9HB15 / potassium two pore domain channel subfamily K member 12  / complex






 

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