ENSG00000184613


Homo sapiens

Features
Gene ID: ENSG00000184613
  
Biological name :NELL2
  
Synonyms : NELL2 / neural EGFL like 2 / Q99435
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q12
Gene start: 44508275
Gene end: 44921848
  
Corresponding Affymetrix probe sets: 203413_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449332
Ensembl peptide - ENSP00000449068
Ensembl peptide - ENSP00000450102
Ensembl peptide - ENSP00000327988
Ensembl peptide - ENSP00000378866
Ensembl peptide - ENSP00000390680
Ensembl peptide - ENSP00000394612
Ensembl peptide - ENSP00000416341
Ensembl peptide - ENSP00000446961
Ensembl peptide - ENSP00000447085
Ensembl peptide - ENSP00000447384
Ensembl peptide - ENSP00000447927
Ensembl peptide - ENSP00000448107
Ensembl peptide - ENSP00000448407
Ensembl peptide - ENSP00000448635
NCBI entrez gene - 4753     See in Manteia.
OMIM - 602320
RefSeq - XM_017019344
RefSeq - NM_001145107
RefSeq - NM_001145108
RefSeq - NM_001145109
RefSeq - NM_001145110
RefSeq - NM_006159
RefSeq - XM_005268905
RefSeq - XM_011538396
RefSeq - XM_017019341
RefSeq - XM_017019342
RefSeq - XM_017019343
RefSeq Peptide - NP_001138582
RefSeq Peptide - NP_006150
RefSeq Peptide - NP_001138579
RefSeq Peptide - NP_001138580
RefSeq Peptide - NP_001138581
swissprot - H0YIT4
swissprot - F8VRQ0
swissprot - F8VVB6
swissprot - F8VXR5
swissprot - F8VZ72
swissprot - F8W1A2
swissprot - F8W1I8
swissprot - H0YHY5
swissprot - Q99435
swissprot - A0A024R0X1
swissprot - H0YI34
Ensembl - ENSG00000184613
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nell2aENSDARG00000090690Danio rerio
 nell2bENSDARG00000062797Danio rerio
 NELL2ENSGALG00000009601Gallus gallus
 Nell2ENSMUSG00000022454Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NELL1 / Q92832 / neural EGFL like 1ENSG0000016597351


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070050 neuron cellular homeostasis ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of commissural axon pathfinding by SLIT and ROBO


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000154134 ROBO3 / Q96MS0 / roundabout guidance receptor 3  / reaction / complex






 

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