ENSMUSG00000022454


Mus musculus

Features
Gene ID: ENSMUSG00000022454
  
Biological name :Nell2
  
Synonyms : Mus musculus NEL-like 2 (Nell2), transcript variant 1, mRNA. / Nell2 / Q61220
  
Possible biological names infered from orthology : neural EGFL like 2 / Q99435
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 95075230
Gene end: 95528559
  
Corresponding Affymetrix probe sets: 10431812 (MoGene1.0st)   1423560_at (Mouse Genome 430 2.0 Array)   1423561_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074751
Ensembl peptide - ENSMUSP00000131665
Ensembl peptide - ENSMUSP00000155436
Ensembl peptide - ENSMUSP00000155490
NCBI entrez gene - 54003     See in Manteia.
MGI - MGI:1858510
RefSeq - XM_011245693
RefSeq - NM_001289653
RefSeq - NM_001356950
RefSeq - NM_001356951
RefSeq - XM_006521163
RefSeq - XM_006521164
RefSeq Peptide - NP_001276582
RefSeq Peptide - NP_001343879
RefSeq Peptide - NP_001343880
swissprot - Q61220
swissprot - Q8BM06
Ensembl - ENSMUSG00000022454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nell2aENSDARG00000090690Danio rerio
 nell2bENSDARG00000062797Danio rerio
 NELL2ENSGALG00000009601Gallus gallus
 NELL2ENSG00000184613Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nell1 / Q2VWQ2 / Protein kinase C-binding protein NELL1 / Q92832* / neural EGFL like 1*ENSMUSG0000005540953


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024731  EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070050 neuron cellular homeostasis ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003008 enhanced long term potentiation "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922]
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Allelic Composition: Arg2tm1Weo/Arg2+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032128 Robo3 / roundabout guidance receptor 3 / Q96MS0*  / complex / reaction






 

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