ENSG00000185518


Homo sapiens

Features
Gene ID: ENSG00000185518
  
Biological name :SV2B
  
Synonyms : Q7L1I2 / SV2B / synaptic vesicle glycoprotein 2B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.1
Gene start: 91099950
Gene end: 91301309
  
Corresponding Affymetrix probe sets: 205551_at (Human Genome U133 Plus 2.0 Array)   232426_at (Human Genome U133 Plus 2.0 Array)   244717_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000332818
Ensembl peptide - ENSP00000377779
Ensembl peptide - ENSP00000443243
Ensembl peptide - ENSP00000450992
NCBI entrez gene - 9899     See in Manteia.
OMIM - 185861
RefSeq - NM_001323036
RefSeq - NM_001323037
RefSeq - NM_001323038
RefSeq - NM_001323039
RefSeq - NM_001323040
RefSeq - NM_014848
RefSeq - XM_017022762
RefSeq - NM_001167580
RefSeq - NM_001323031
RefSeq - NM_001323032
RefSeq - NM_001323033
RefSeq - NM_001323034
RefSeq - XM_005254998
RefSeq - XM_017022761
RefSeq Peptide - NP_001309961
RefSeq Peptide - NP_001309963
RefSeq Peptide - NP_001309965
RefSeq Peptide - NP_001309966
RefSeq Peptide - NP_001309967
RefSeq Peptide - NP_001309968
RefSeq Peptide - NP_001309969
RefSeq Peptide - NP_055663
RefSeq Peptide - NP_001309962
RefSeq Peptide - NP_001161052
RefSeq Peptide - NP_001309960
swissprot - Q7L1I2
Ensembl - ENSG00000185518
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sv2baENSDARG00000057427Danio rerio
 sv2bbENSDARG00000060711Danio rerio
 SV2BENSGALG00000030250Gallus gallus
 Sv2bENSMUSG00000053025Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SV2A / Q7L0J3 / synaptic vesicle glycoprotein 2AENSG0000015916464
SV2C / Q496J9 / synaptic vesicle glycoprotein 2CENSG0000012201261
SVOP / Q8N4V2 / SV2 related proteinENSG0000016611119
SVOPL / Q8N434 / SVOP likeENSG0000015770318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001646  Pentapeptide repeat
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR022308  Synaptic vesicle protein SV2
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle TAS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Toxicity of botulinum toxin type D (BoNT/D)
Toxicity of botulinum toxin type A (BoNT/A)
Toxicity of botulinum toxin type F (BoNT/F)
Toxicity of botulinum toxin type E (BoNT/E)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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