ENSG00000159164


Homo sapiens

Features
Gene ID: ENSG00000159164
  
Biological name :SV2A
  
Synonyms : Q7L0J3 / SV2A / synaptic vesicle glycoprotein 2A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.2
Gene start: 149903318
Gene end: 149917882
  
Corresponding Affymetrix probe sets: 203069_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358141
Ensembl peptide - ENSP00000358142
NCBI entrez gene - 9900     See in Manteia.
OMIM - 185860
RefSeq - XM_017002992
RefSeq - NM_001328674
RefSeq - NM_001328675
RefSeq - NM_014849
RefSeq Peptide - NP_001315604
RefSeq Peptide - NP_055664
RefSeq Peptide - NP_001315603
swissprot - Q7L0J3
Ensembl - ENSG00000159164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sv2aENSDARG00000059945Danio rerio
 Sv2aENSMUSG00000038486Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SV2C / Q496J9 / synaptic vesicle glycoprotein 2CENSG0000012201263
SV2B / Q7L1I2 / synaptic vesicle glycoprotein 2BENSG0000018551859
SVOP / Q8N4V2 / SV2 related proteinENSG0000016611117
SVOPL / Q8N434 / SVOP likeENSG0000015770317


Protein motifs (from Interpro)
Interpro ID Name
 IPR001646  Pentapeptide repeat
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR022308  Synaptic vesicle protein SV2
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0014052 regulation of gamma-aminobutyric acid secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0008021 synaptic vesicle TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030672 synaptic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0019901 protein kinase binding ISS
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Toxicity of botulinum toxin type D (BoNT/D)
Toxicity of botulinum toxin type A (BoNT/A)
Toxicity of botulinum toxin type F (BoNT/F)
Toxicity of botulinum toxin type E (BoNT/E)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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