ENSG00000185760


Homo sapiens

Features
Gene ID: ENSG00000185760
  
Biological name :KCNQ5
  
Synonyms : KCNQ5 / potassium voltage-gated channel subfamily Q member 5 / Q9NR82
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q13
Gene start: 72621792
Gene end: 73198851
  
Corresponding Affymetrix probe sets: 223891_at (Human Genome U133 Plus 2.0 Array)   244623_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384453
Ensembl peptide - ENSP00000486187
Ensembl peptide - ENSP00000485743
Ensembl peptide - ENSP00000414829
Ensembl peptide - ENSP00000409861
Ensembl peptide - ENSP00000391971
Ensembl peptide - ENSP00000388098
Ensembl peptide - ENSP00000385501
Ensembl peptide - ENSP00000345055
Ensembl peptide - ENSP00000347326
Ensembl peptide - ENSP00000347853
Ensembl peptide - ENSP00000359419
Ensembl peptide - ENSP00000359425
NCBI entrez gene - 56479     See in Manteia.
OMIM - 607357
RefSeq - XM_017011058
RefSeq - NM_001160130
RefSeq - NM_001160132
RefSeq - NM_001160133
RefSeq - NM_001160134
RefSeq - NM_019842
RefSeq Peptide - NP_062816
RefSeq Peptide - NP_001153605
RefSeq Peptide - NP_001153606
RefSeq Peptide - NP_001153602
RefSeq Peptide - NP_001153604
swissprot - A0A0A0MSD9
swissprot - A0A0A0MSC0
swissprot - A0A0A0MRC8
swissprot - F8WEA4
swissprot - A6PVT7
swissprot - H0Y3Z0
swissprot - Q9NR82
swissprot - A6PVT8
swissprot - A0A0A0MT07
Ensembl - ENSG00000185760
  
Related genetic diseases (OMIM): 617601 - Mental retardation, autosomal dominant 46, 617601
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnq5aENSDARG00000069954Danio rerio
 kcnq5bENSDARG00000069953Danio rerio
 KCNQ5ENSGALG00000037249Gallus gallus
 Kcnq5ENSMUSG00000028033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNQ4 / P56696 / potassium voltage-gated channel subfamily Q member 4ENSG0000011701343
KCNQ2 / O43526 / potassium voltage-gated channel subfamily Q member 2ENSG0000007504342
KCNQ3 / O43525 / potassium voltage-gated channel subfamily Q member 3ENSG0000018415638
KCNQ1 / P51787 / potassium voltage-gated channel subfamily Q member 1ENSG0000005391827


Protein motifs (from Interpro)
Interpro ID Name
 IPR003937  Potassium channel, voltage dependent, KCNQ
 IPR005821  Ion transport domain
 IPR013821  Potassium channel, voltage dependent, KCNQ, C-terminal
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030118 clathrin coat IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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