ENSG00000186866


Homo sapiens

Features
Gene ID: ENSG00000186866
  
Biological name :POFUT2
  
Synonyms : POFUT2 / protein O-fucosyltransferase 2 / Q9Y2G5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.3
Gene start: 45263928
Gene end: 45287898
  
Corresponding Affymetrix probe sets: 1555546_a_at (Human Genome U133 Plus 2.0 Array)   207448_at (Human Genome U133 Plus 2.0 Array)   207449_s_at (Human Genome U133 Plus 2.0 Array)   209578_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478168
Ensembl peptide - ENSP00000407635
Ensembl peptide - ENSP00000482216
Ensembl peptide - ENSP00000329682
Ensembl peptide - ENSP00000335427
Ensembl peptide - ENSP00000339613
NCBI entrez gene - 23275     See in Manteia.
OMIM - 610249
RefSeq - XM_017028307
RefSeq - XM_011529505
RefSeq - XM_011529506
RefSeq - XM_011529507
RefSeq - XM_011529510
RefSeq - XM_011529513
RefSeq - XM_017028306
RefSeq - NM_015227
RefSeq - NM_133635
RefSeq - XM_006723981
RefSeq - XM_011529504
RefSeq Peptide - NP_056042
RefSeq Peptide - NP_598368
swissprot - H7C2T5
swissprot - S6FW71
swissprot - A0A0C4DGX7
swissprot - Q9Y2G5
Ensembl - ENSG00000186866
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pofut2ENSDARG00000045175Danio rerio
 POFUT2ENSGALG00000006141Gallus gallus
 Pofut2ENSMUSG00000020260Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019378  GDP-fucose protein O-fucosyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006004 fucose metabolic process IEA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0036065 fucosylation IEA
 biological_processGO:0036066 protein O-linked fucosylation TAS
 biological_processGO:0051046 regulation of secretion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0008417 fucosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046922 peptide-O-fucosyltransferase activity TAS


Pathways (from Reactome)
Pathway description
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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