ENSG00000187726


Homo sapiens

Features
Gene ID: ENSG00000187726
  
Biological name :DNAJB13
  
Synonyms : DNAJB13 / DnaJ heat shock protein family (Hsp40) member B13 / P59910
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 73950319
Gene end: 73970366
  
Corresponding Affymetrix probe sets: 230936_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000344431
Ensembl peptide - ENSP00000438576
Ensembl peptide - ENSP00000439711
Ensembl peptide - ENSP00000440778
NCBI entrez gene - 374407     See in Manteia.
OMIM - 610263
RefSeq - XM_017017678
RefSeq - NM_153614
RefSeq - XM_017017675
RefSeq - XM_017017676
RefSeq - XM_017017677
RefSeq - XM_005273984
RefSeq - XM_011545004
RefSeq - XM_011545005
RefSeq - XM_011545007
RefSeq - XM_011545009
RefSeq - XM_011545015
RefSeq Peptide - NP_705842
swissprot - P59910
swissprot - H0YFX2
Ensembl - ENSG00000187726
  
Related genetic diseases (OMIM): 617091 - Ciliary dyskinesia, primary, 34, 617091
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajb13ENSDARG00000043157Danio rerio
 DNAJB13ENSGALG00000017317Gallus gallus
 Q80Y75ENSMUSG00000030708Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNAJB1 / P25685 / DnaJ heat shock protein family (Hsp40) member B1ENSG0000013200251
DNAJB5 / O75953 / DnaJ heat shock protein family (Hsp40) member B5ENSG0000013709450
DNAJB4 / Q9UDY4 / DnaJ heat shock protein family (Hsp40) member B4ENSG0000016261648
DNAJB6 / O75190 / DnaJ heat shock protein family (Hsp40) member B6ENSG0000010599327
DNAJB8 / Q8NHS0 / DnaJ heat shock protein family (Hsp40) member B8ENSG0000017940721
DNAJB7 / Q7Z6W7 / DnaJ heat shock protein family (Hsp40) member B7ENSG0000017240421
DNAJB2 / P25686 / DnaJ heat shock protein family (Hsp40) member B2ENSG0000013592420
DNAJB9 / Q9UBS3 / DnaJ heat shock protein family (Hsp40) member B9ENSG0000012859017


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR002939  Chaperone DnaJ, C-terminal
 IPR008971  HSP40/DnaJ peptide-binding
 IPR018253  DnaJ domain, conserved site
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:1904158 axonemal central apparatus assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0031514 motile cilium IEA
 cellular_componentGO:0036126 sperm flagellum IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097224 sperm connecting piece ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000007 Autosomal recessive inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators]
Show

 HP:0002205 Recurrent respiratory infections 
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr