ENSG00000188611


Homo sapiens

Features
Gene ID: ENSG00000188611
  
Biological name :ASAH2
  
Synonyms : ASAH2 / N-acylsphingosine amidohydrolase 2 / Q9NR71
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.23
Gene start: 50182778
Gene end: 50248610
  
Corresponding Affymetrix probe sets: 229793_at (Human Genome U133 Plus 2.0 Array)   231791_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392766
Ensembl peptide - ENSP00000388206
Ensembl peptide - ENSP00000476403
Ensembl peptide - ENSP00000476827
Ensembl peptide - ENSP00000329886
Ensembl peptide - ENSP00000378897
NCBI entrez gene - 56624     See in Manteia.
OMIM - 611202
RefSeq - XM_017016436
RefSeq - NM_001143974
RefSeq - NM_019893
RefSeq - XM_011539970
RefSeq - XM_011539971
RefSeq - XM_011539972
RefSeq - XM_011539973
RefSeq - XM_017016435
RefSeq Peptide - NP_001137446
RefSeq Peptide - NP_063946
swissprot - A0A0C4DFQ8
swissprot - E9PBM9
swissprot - V9GY52
swissprot - Q9NR71
swissprot - V9GYJ5
Ensembl - ENSG00000188611
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asah2ENSDARG00000012829Danio rerio
 ENSGALG00000003751Gallus gallus
 Asah2ENSMUSG00000024887Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASAH2B / P0C7U1 / N-acylsphingosine amidohydrolase 2BENSG0000020414718


Protein motifs (from Interpro)
Interpro ID Name
 IPR006823  Neutral/alkaline nonlysosomal ceramidase
 IPR031329  Neutral/alkaline non-lysosomal ceramidase, N-terminal
 IPR031331  Neutral/alkaline non-lysosomal ceramidase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006672 ceramide metabolic process TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017040 N-acylsphingosine amidohydrolase activity IEA
 molecular_functionGO:0102121 ceramidase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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