ENSMUSG00000024887


Mus musculus

Features
Gene ID: ENSMUSG00000024887
  
Biological name :Asah2
  
Synonyms : Asah2 / Neutral ceramidase Neutral ceramidase soluble form / Q9JHE3
  
Possible biological names infered from orthology : ASAH2B / N-acylsphingosine amidohydrolase 2 / N-acylsphingosine amidohydrolase 2B / P0C7U1 / Q9NR71
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C1
Gene start: 31984654
Gene end: 32061469
  
Corresponding Affymetrix probe sets: 10467041 (MoGene1.0st)   1425994_a_at (Mouse Genome 430 2.0 Array)   1450726_at (Mouse Genome 430 2.0 Array)   1458849_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093830
NCBI entrez gene - 54447     See in Manteia.
MGI - MGI:1859310
RefSeq - XM_011247290
RefSeq - NM_018830
RefSeq - XM_011247286
RefSeq - XM_011247287
RefSeq - XM_011247289
RefSeq - XM_011247283
RefSeq - XM_011247284
RefSeq - XM_011247285
RefSeq Peptide - NP_061300
swissprot - Q9JHE3
swissprot - B9EHG7
Ensembl - ENSMUSG00000024887
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asah2ENSDARG00000012829Danio rerio
 ENSGALG00000003751Gallus gallus
 ASAH2ENSG00000188611Homo sapiens
 ASAH2BENSG00000204147Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006823  Neutral/alkaline nonlysosomal ceramidase
 IPR031329  Neutral/alkaline non-lysosomal ceramidase, N-terminal
 IPR031331  Neutral/alkaline non-lysosomal ceramidase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0010033 response to organic substance IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017040 N-acylsphingosine amidohydrolase activity IDA
 molecular_functionGO:0102121 ceramidase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Scn5atm1Agrc/Scn5a+
Genetic Background: involves: 129/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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