ENSG00000188677


Homo sapiens

Features
Gene ID: ENSG00000188677
  
Biological name :PARVB
  
Synonyms : PARVB / parvin beta / Q9HBI1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 43999211
Gene end: 44172949
  
Corresponding Affymetrix probe sets: 204629_at (Human Genome U133 Plus 2.0 Array)   216253_s_at (Human Genome U133 Plus 2.0 Array)   229822_at (Human Genome U133 Plus 2.0 Array)   37965_at (Human Genome U133 Plus 2.0 Array)   37966_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482511
Ensembl peptide - ENSP00000384353
Ensembl peptide - ENSP00000384515
Ensembl peptide - ENSP00000393758
Ensembl peptide - ENSP00000342492
NCBI entrez gene - 29780     See in Manteia.
OMIM - 608121
RefSeq - XM_017028792
RefSeq - NM_001003828
RefSeq - NM_001243385
RefSeq - NM_001243386
RefSeq - NM_013327
RefSeq - XM_005261596
RefSeq Peptide - NP_001230315
RefSeq Peptide - NP_001230314
RefSeq Peptide - NP_001003828
RefSeq Peptide - NP_037459
swissprot - A0A087WZB5
swissprot - B0QYP8
swissprot - Q9HBI1
Ensembl - ENSG00000188677
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parvbENSDARG00000019117Danio rerio
 PARVBENSGALG00000014201Gallus gallus
 ParvbENSMUSG00000022438Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARVA / parvin alphaENSG0000019770263
PARVG / Q9HBI0 / parvin gammaENSG0000013896434


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR028433  Parvin
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030031 cell projection assembly IMP
 biological_processGO:0030032 lamellipodium assembly IMP
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0071963 establishment or maintenance of cell polarity regulating cell shape IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030017 sarcomere IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Cell-extracellular matrix interactions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000072110 ACTN1 / P12814 / actinin alpha 1  / reaction / complex
 ENSG00000129675 Q15052 / ARHGEF6 / Rac/Cdc42 guanine nucleotide exchange factor 6  / complex / reaction






 

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