ENSDARG00000019117


Danio rerio

Features
Gene ID: ENSDARG00000019117
  
Biological name :parvb
  
Synonyms : parvb / parvin, beta
  
Possible biological names infered from orthology : Q9ES46 / Q9HBI1
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 5035343
Gene end: 5063523
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000012119
Ensembl peptide - ENSDARP00000127883
Ensembl peptide - ENSDARP00000129149
NCBI entrez gene - 325686     See in Manteia.
swissprot - Q6PC42
swissprot - X1WCE0
swissprot - X1WFZ4
ZFIN ID - ZDB-GENE-030131-4411
Ensembl - ENSDARG00000019117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PARVBENSGALG00000014201Gallus gallus
 PARVBENSG00000188677Homo sapiens
 ParvbENSMUSG00000022438Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
parvaa / parvin, alpha a / PARVA* / Q9EPC1* / parvin alpha*ENSDARG0000004371067
parvab / parvin, alpha b / PARVA* / Q9EPC1* / parvin alpha*ENSDARG0000003562966
parvg / parvin, gamma / Q9ERD8* / Q9HBI0* / Gamma-parvin *ENSDARG0000006771131


Protein motifs (from Interpro)
Interpro ID Name
 IPR001715  Calponin homology domain
 IPR028433  Parvin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IMP
 biological_processGO:0008016 regulation of heart contraction IMP
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 cellular_componentGO:0030018 Z disc IDA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle non-contractile , abnormal
cardiac ventricle decreased contractility , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000473 trunk musculature trunk musculature skeletal muscle cell retracted , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006683 arhgef6 / Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 / Q15052* / Rac/Cdc42 guanine nucleotide exchange factor 6*  / complex / reaction
 ENSDARG00000007219 actn1 / actinin, alpha 1 / P12814* / Q7TPR4* / Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA.*  / complex / reaction






 

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