ENSDARG00000007219


Danio rerio

Features
Gene ID: ENSDARG00000007219
  
Biological name :actn1
  
Synonyms : actinin, alpha 1 / actn1
  
Possible biological names infered from orthology : Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA. / P12814 / Q7TPR4
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 36321088
Gene end: 36391502
  
Corresponding Affymetrix probe sets: Dr.25774.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123299
Ensembl peptide - ENSDARP00000090990
Ensembl peptide - ENSDARP00000120755
Ensembl peptide - ENSDARP00000123185
NCBI entrez gene - 560400     See in Manteia.
RefSeq - XM_009307474
RefSeq - XM_009307476
RefSeq - NM_001168286
RefSeq - XM_009307475
RefSeq Peptide - NP_001161758
swissprot - F1QER4
swissprot - B8JHU4
ZFIN ID - ZDB-GENE-081113-4
Ensembl - ENSDARG00000007219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTN1ENSGALG00000042458Gallus gallus
 ACTN1ENSG00000072110Homo sapiens
 Actn1ENSMUSG00000015143Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
actn4 / actinin, alpha 4 / O43707*ENSDARG0000009978685
actn3b / actinin alpha 3b / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000000143179
actn2b / actinin, alpha 2b / ACTN2* / P35609* / Q9JI91* / actinin alpha 2* / Alpha-actinin-2 *ENSDARG0000007109078
actn3a / actinin alpha 3a / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000001375578
sptbn2 / spectrin, beta, non-erythrocytic 2 / O15020*ENSDARG0000005395630
sptb / spectrin, beta, erythrocytic / P11277*ENSDARG0000003049029
sptbn5 / spectrin, beta, non-erythrocytic 5 / Q9NRC6*ENSDARG0000009768329
sptbn1 / spectrin, beta, non-erythrocytic 1 / Q01082* / Q62261* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG0000010288328
SPTBN4 / si:ch73-262h23.4 / Q9H254* / spectrin beta, non-erythrocytic 4*ENSDARG0000009262424
sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...ENSDARG0000001923118
si:dkey-27p18.5 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000000686244
si:zfos-1837d3.1 / Q62261* / Q01082* / SPTBN1* / spectrin beta, non-erythrocytic 1* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG000001054282
si:ch73-262h23.4 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000001119421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR014837  EF-hand, Ca insensitive
 IPR018159  Spectrin/alpha-actinin
 IPR018247  EF-Hand 1, calcium-binding site
 IPR026921  Alpha-actinin 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051764 actin crosslink formation IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019117 parvb / parvin, beta / Q9ES46* / Q9HBI1*  / complex / reaction






 

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