ENSDARG00000099786


Danio rerio

Features
Gene ID: ENSDARG00000099786
  
Biological name :actn4
  
Synonyms : actinin, alpha 4 / actn4
  
Possible biological names infered from orthology : Alpha-actinin-4 / O43707 / P57780
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 43398317
Gene end: 43510872
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000132801
Ensembl peptide - ENSDARP00000150996
Ensembl peptide - ENSDARP00000153540
NCBI entrez gene - 322221     See in Manteia.
RefSeq - NM_199586
RefSeq Peptide - NP_955880
swissprot - H9GX78
swissprot - Q7SYE2
ZFIN ID - ZDB-GENE-030131-940
Ensembl - ENSDARG00000099786
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTN4ENSG00000130402Homo sapiens
 Actn4ENSMUSG00000054808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
actn1 / actinin, alpha 1 / P12814* / Q7TPR4* / Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA.*ENSDARG0000000721983
actn3b / actinin alpha 3b / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000000143176
actn3a / actinin alpha 3a / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000001375576
actn2b / actinin, alpha 2b / ACTN2* / P35609* / Q9JI91* / actinin alpha 2* / Alpha-actinin-2 *ENSDARG0000007109075
sptbn2 / spectrin, beta, non-erythrocytic 2 / O15020*ENSDARG0000005395630
sptbn5 / spectrin, beta, non-erythrocytic 5 / Q9NRC6*ENSDARG0000009768329
sptb / spectrin, beta, erythrocytic / P11277*ENSDARG0000003049029
sptbn1 / spectrin, beta, non-erythrocytic 1 / Q01082* / Q62261* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG0000010288328
SPTBN4 / si:ch73-262h23.4 / Q9H254* / spectrin beta, non-erythrocytic 4*ENSDARG0000009262423
sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...ENSDARG0000001923118
si:dkey-27p18.5 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000000686244
si:zfos-1837d3.1 / Q62261* / Q01082* / SPTBN1* / spectrin beta, non-erythrocytic 1* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG000001054282
si:ch73-262h23.4 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000001119421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR014837  EF-hand, Ca insensitive
 IPR018159  Spectrin/alpha-actinin
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051764 actin crosslink formation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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