ENSG00000188846


Homo sapiens

Features
Gene ID: ENSG00000188846
  
Biological name :RPL14
  
Synonyms : P50914 / ribosomal protein L14 / RPL14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.1
Gene start: 40457292
Gene end: 40468587
  
Corresponding Affymetrix probe sets: 200074_s_at (Human Genome U133 Plus 2.0 Array)   213588_x_at (Human Genome U133 Plus 2.0 Array)   219138_at (Human Genome U133 Plus 2.0 Array)   229544_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391446
Ensembl peptide - ENSP00000402476
Ensembl peptide - ENSP00000345156
Ensembl peptide - ENSP00000379506
NCBI entrez gene - 9045     See in Manteia.
OMIM - 617414
RefSeq - NM_003973
RefSeq - NM_001034996
RefSeq Peptide - NP_001030168
RefSeq Peptide - NP_003964
swissprot - P50914
swissprot - E7EPB3
swissprot - F8WDZ7
Ensembl - ENSG00000188846
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl14ENSDARG00000103433Danio rerio
 ENSGALG00000043379Gallus gallus
 Rpl14ENSMUSG00000025794Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002784  Ribosomal protein L14e domain
 IPR008991  Translation protein SH3-like domain superfamily
 IPR014722  Ribosomal protein L2, domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0042273 ribosomal large subunit biogenesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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