ENSG00000189280


Homo sapiens

Features
Gene ID: ENSG00000189280
  
Biological name :GJB5
  
Synonyms : gap junction protein beta 5 / GJB5 / O95377
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.3
Gene start: 34755047
Gene end: 34758512
  
Corresponding Affymetrix probe sets: 206156_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000340811
NCBI entrez gene - 2709     See in Manteia.
OMIM - 604493
RefSeq - NM_005268
RefSeq - XM_005270751
RefSeq Peptide - NP_005259
swissprot - O95377
Ensembl - ENSG00000189280
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cx34.4ENSDARG00000075854Danio rerio
 Gjb5ENSMUSG00000042357Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GJB4 / Q9NTQ9 / gap junction protein beta 4ENSG0000018943359
GJB3 / O75712 / gap junction protein beta 3ENSG0000018891051
GJB7 / Q6PEY0 / gap junction protein beta 7ENSG0000016441145
GJB1 / P08034 / gap junction protein beta 1ENSG0000016956244
GJB6 / O95452 / gap junction protein beta 6ENSG0000012174242
GJB2 / P29033 / gap junction protein beta 2ENSG0000016547439
GJD4 / Q96KN9 / gap junction protein delta 4ENSG0000017729125
GJC3 / Q8NFK1 / gap junction protein gamma 3ENSG0000017640225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002271  Gap junction beta-5 protein (Cx30.3)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0060707 trophoblast giant cell differentiation IEA
 biological_processGO:0060708 spongiotrophoblast differentiation IEA
 biological_processGO:0060713 labyrinthine layer morphogenesis IEA
 biological_processGO:1905867 epididymis development IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA


Pathways (from Reactome)
Pathway description
Gap junction assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr