ENSG00000189308


Homo sapiens

Features
Gene ID: ENSG00000189308
  
Biological name :LIN54
  
Synonyms : LIN54 / lin-54 DREAM MuvB core complex component / Q6MZP7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.22
Gene start: 82909973
Gene end: 83012926
  
Corresponding Affymetrix probe sets: 235809_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423475
Ensembl peptide - ENSP00000421651
Ensembl peptide - ENSP00000425844
Ensembl peptide - ENSP00000427413
Ensembl peptide - ENSP00000341947
Ensembl peptide - ENSP00000398265
Ensembl peptide - ENSP00000407139
Ensembl peptide - ENSP00000421045
NCBI entrez gene - 132660     See in Manteia.
OMIM - 613367
RefSeq - XM_017007730
RefSeq - NM_001115008
RefSeq - NM_001288996
RefSeq - NM_001288997
RefSeq - NM_194282
RefSeq - XM_005262750
RefSeq - XM_006714081
RefSeq - XM_017007728
RefSeq - XM_017007729
RefSeq - NM_001115007
RefSeq Peptide - NP_001275926
RefSeq Peptide - NP_001108479
RefSeq Peptide - NP_001108480
RefSeq Peptide - NP_919258
RefSeq Peptide - NP_001275925
swissprot - Q6MZP7
swissprot - D6REW4
swissprot - A0A024RDD8
Ensembl - ENSG00000189308
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lin54ENSDARG00000063194Danio rerio
 LIN54ENSGALG00000011133Gallus gallus
 Lin54ENSMUSG00000035310Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y4I5 / TESMIN / testis expressed metallothionein like proteinENSG0000013274922


Protein motifs (from Interpro)
Interpro ID Name
 IPR005172  CRC domain
 IPR028307  Lin-54 family
 IPR033467  Tesmin/TSO1-like CXC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051726 regulation of cell cycle TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
Activation of E2F1 target genes at G1/S
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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